boswellia drug interactions


Rheumatology (Oxford) 2011;50(5):911-920. J Ethnopharmacol 1993;38:1139. Efficacy of food supplement Acidif plus in the treatment of uncomplicated UTIs in women: a pilot observational study. View abstract. View abstract. How much Boswellia should I take for arthritis? Agents Actions 1987;22(1-2):99-105. There's no standard dosage of Boswellia for any medical condition as there's such wide variation among products that contain it. Planta Med 2004;70(12):1155-1160. 2016 Mar;29(1):140-6.

Minerva Gastroenterol Dietol 2019;65(1):30-5. View abstract.

Eshaghian R, Mazaheri M, Ghanadian M, Rouholamin S, Feizi A, Babaeian M. The effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) on heavy menstrual bleeding: a randomized, placebo-controlled, clinical trial.

Badria FA, Mohammed EA El-Badrawy MK El-Desouky M. Natural leukotriene inhibitor from Boswellia: A potential new alternative for treating bronchial asthma. View abstract. Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.

2022 Dotdash Media, Inc. All rights reserved. Pungle P, Banavalikar M, Suthar A, et al. Eur Rev Med Pharmacol Sci. View abstract. View abstract. Select a condition to view a list of vitamins. View abstract. It could also improve gut health.

It's been used in traditional health systems for centuries.

View abstract. View abstract.

Aloe Vera: Benefits, Side Effects, Dosage, Interactions, nonsteroidal anti-inflammatory drugs (NSAID), Oral herbal therapies for treating osteoarthritis, Functional study on Boswellia phytosome as complementary intervention in asthmatic patients, Symptomatic uncomplicated diverticular disease management: an innovative food-grade formulation of, Boswellic acids and their role in chronic inflammatory diseases, Effect of Boswellia serrata supplementation on blood lipid, hepatic enzymes and fructosamine levels in type 2 diabetic patients, P-glycoprotein and its role in drug-drug interactions, An evaluation of potential inhibition of CYP3A4/5 and CYP2C9 enzymatic activity by Boswellia serrata extract, Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial, HERB working group. Safety and toxicological evaluation of a novel, standardized 3-O-acetyl-11-keto-beta-boswellic acid (AKBA)-enriched Boswellia serrata extract (5-Loxin). Boswellia can be found in many health food stores. Memorial Sloan Kettering Cancer Center. Boswellia has no known mild interactions with other drugs. Don't Overlook These Natural Asthma Treatments, How Quercetin Is Used to Help Allergies and High Blood Pressure.

Iran J Pharm Res.

Mol.Cancer Ther 2005;4(3):381-388.

doi:10.1002/14651858.CD002947.pub2.

Kirste S, Treier M, Wehrle SJ, et al. Allergic contact dermatitis from Boswellia serrata extract in a naturopathic cream.

2002;152(15-16):373-378. Mehrzadi S, Tavakolifar B, Huseini HF, Mosavat SH, Heydari M. The Effects of Boswellia serrata Gum Resin on the Blood Glucose and Lipid Profile of Diabetic Patients: A Double-Blind Randomized Placebo-Controlled Clinical Trial. Phytother Res 2019;33(5):1457-68. View abstract. 1996;117(4):615-618.

2019;20(8):16191632. In arthritis studies, 100 mg to 1000 mg of Boswellia extracts or 300 mg to 600 mg of Boswellia with other herbs were used daily. Effects ofBoswellia SerrataRoxb.

View abstract. Curr Med Chem 2006;13(28):3359-3369. View abstract.

Identification of lupeolic acid, a novel pentacyclic triterpene. A double-blind, randomized, placebo controlled clinical study evaluates the early efficacy of aflapin in subjects with osteoarthritis of knee. Pregnant and nursing women shouldn't take it.

Janssen G, Bode U, Breu H, et al. 2020;72(2):70-74.

View abstract.

Int J Med Sci 2011;8:615-22.

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View abstract.

Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial.

View abstract.

These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research.

However, some studies suggest taking 300 milligrams (mg) to 400 mg three times a day of an extract containing 60% boswellic acids for inflammatory diseases or asthma.

Notarnicola A, Maccagnano G, Moretti L, et al. This information may not fit your specific health circumstances.

Ferrara T, De Vincentiis G, Di Pierro F. Functional study on Boswellia phytosome as complementary intervention in asthmatic patients. The anti-inflammatory effects of Boswellia have led some researchers to suggest chewing Boswellia gum to reduce mild lung symptoms of COVID-19. Roy, S., Khanna, S., Krishnaraju, A. V., Subbaraju, G. V., Yasmin, T., Bagchi, D., and Sen, C. K. Regulation of vascular responses to inflammation: inducible matrix metalloproteinase-3 expression in human microvascular endothelial cells is sensitive to antiinflammatory Boswellia.

Therefore, before using this product, tell your doctor or pharmacist of all the products you use.

Sterk, V., Buchele, B., and Simmet, T. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers.

Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study.

Galeone, G., Spadavecchia, R., Balducci, M. T., and Pagliarulo, V. [The role of Proxelan in the treatment of chronic prostatitis.

Boswellia has no known severe interactions with other drugs. Flavin, D. F. A lipoxygenase inhibitor in breast cancer brain metastases. View abstract.



Information from this source is evidence-based and objective, and without commercial influence.

Drugs Context.

There's some evidence to suggest Boswellia may help with arthritis, asthma, and inflammatory bowel conditions. View abstract. Barletta C, Paccone M, Uccello N, et al.

2003;27(1):67-75.

View abstract.

View abstract.

Symptomatic uncomplicated diverticular disease management: an innovative food-grade formulation ofCurcuma longaandBoswellia serrata extracts. It is often taken by mouth or applied to the skin for: Some studies suggest that Boswellia may have anti-inflammatory and antioxidant effects.

Dt rztebl 1997;94:1197.

Kulkarni RR, Patki PS, Jog VP, et al.

All rights reserved. Zhongguo Gu.Shang 2009;22(12):920-922.

2000;63(8):1058-1061. View abstract.



Boswellia can also interact with some drugs, so it's vital that you talk with your healthcare provider before taking it. Dermatol Ther 2010;23:S28-32. Eur Rev Med Pharmacol Sci.

Although some natural products may reduce inflammation, don't use them in place of any medications prescribed by your healthcare provider.

Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. They suggested that the two herbs together might have a protective effect on the lining of the gut.

Chopra A, Lavin P, Patwardhan B, Chitre D. Randomized double blind trial of an an aayurvedic plant derived formulation for treatment of rheumatoid arthritis.

Am J Gastroenterol 2009;104(1):235-241. See additional information. But more research is needed to confirm these benefits.

Akihisa, T., Tabata, K., Banno, N., Tokuda, H., Nishimura, R., Nakamura, Y., Kimura, Y., Yasukawa, K., and Suzuki, T. Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri.

Eur J Med Res.

View abstract. Boswellic acids and their role in chronic inflammatory diseases. Suggested Dosing: Follow manufacturer's instructions, 300-500 mg orally two to three times daily, Gum Resin preparation: 350 mg three times daily orally, Generally 300-500 mg orally two to three times daily, higher in inflammatory bowel disease (. Zhao, W., Entschladen, F., Liu, H., Niggemann, B., Fang, Q., Zaenker, K. S., and Han, R. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. Azadmehr A, Ziaee A, Ghanei L, Fallah Huseini H, Hajiaghaee R, Tavakoli-Far B, Kordafshari G. A Randomized Clinical Trial Study: Anti-Oxidant, Anti-hyperglycemic and Anti-Hyperlipidemic Effects of Olibanum Gum in Type 2 Diabetic Patients.

Cancer Detect.Prev.

Anticancer Res.

People who are pregnant, breastfeeding, or have gastroesophageal reflux disease likely should not take Boswellia at all.

Boswellia may interact with nonsteroidal anti-inflammatory drugs (NSAID) like ibuprofen.

2006;8(3-4):653-660. Effects of gum resin of Boswellia serrata in patients with chronic colitis. 2015 Oct;19(19):3757-62. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Contact Dermatitis 2004;51:91-2. Aust Prescr 2014;37:137-9.doi.org/10.18773/austprescr.2014.050, Roe AL, Wilcox R, Price JM, et al. Ammon, H. P., Mack, T., Singh, G. B., and Safayhi, H. Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata. View abstract. View abstract. How long does it take for Boswellia to relieve arthritis?

Neurology 2001;56:1219-21. Minerva Ginecol. A small 2015 study said Boswellia may help reduce the need for inhaler use in people with asthma.

Dietary ingredients requiring further research before evidence-based recommendations can be made for their use as an approach to mitigating pain, Boswellia serrata, a potential antiinflammatory agent: an overview.

Sharma S, Thawani V, Hingorani L, et al. Schweizer, S., von Brocke, A. F., Boden, S. E., Bayer, E., Ammon, H. P., and Safayhi, H. Workup-dependent formation of 5-lipoxygenase inhibitory boswellic acid analogues. It could be safe when applied to the skin for up to five weeks.

View abstract.

Two case reportsdescribedangerously high INR in people taking the blood thinner Coumadin (warfarin) and Boswellia. View abstract.

View abstract. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns, or for more information about this medicine.

2006;29(9):1976-1979.

This information does not contain all possible interactions or adverse effects. Planta Med 2002;68(5):397-401. OTHER NAME(S): Arbre Oliban Indien, Boswella, Boswellin, Boswel.

Sengupta K, Krishnaraju AV, Vishal AA, et al. Joos, S., Rosemann, T., Szecsenyi, J., Hahn, E. G., Willich, S. N., and Brinkhaus, B.

Evidence for the efficacy of complementary and alternative medicines in the management of osteoarthritis: a systematic review.

Oral administration of a lecithin-based delivery form of boswellic acids (Casperome?) Phytomedicine 1996;3(1):77-80.

Streffer JR, Bitzer M, Schabet M, et al. Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee.

J Immunol 3-1-2006;176(5):3127-3140. doi:10.1007/978-3-319-41334-1_13, Ahangarpour A, Heidari H, Fatemeh RA, et al. View abstract. Wildfeuer A, Neu IS, Safayhi H, et al. What Other Drugs Interact with Boswellia?

View abstract. View abstract.

J Nat.Prod.

BMC.Complement Altern Med 2006;6:19. A double-blind, randomized, placebo-controlled, multicenter trial. It may also interact with these drugs: It's important to talk to your healthcare provider before using Boswellia. After 30 days, 21 of 27 people reported less pain. Here's a look at findings from the available research: In a 2014 research review, experts analyzed trials of herbs used for osteoarthritis.

10-5-2003;795(2):355-362. Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis.

Holtmeier W, Zeusem S, Preib J, et al.

Buchele, B. and Simmet, T. Analysis of 12 different pentacyclic triterpenic acids from frankincense in human plasma by high-performance liquid chromatography and photodiode array detection.

Z Rheumatol 1998;57:11-6. Br J Pharmacol 2004;141:223-32.

Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee. Boswellia is the extract of the Boswellia serrata tree. Check with your physician for additional information about side effects. Boswellia serrata is a tree native to India, Africa, and the Arabian Peninsula.

Pedretti A, Capezzera, Zane C, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. View abstract. Sailer, E. R., Subramanian, L. R., Rall, B., Hoernlein, R. F., Ammon, H. P., and Safayhi, H. Acetyl-11-keto-beta-boswellic acid (AKBA): structure requirements for binding and 5-lipoxygenase inhibitory activity. 2014;2014(5):CD002947.

Content is reviewed before publication and upon substantial updates. Boswellic acids in the palliative therapy of children with progressive or relapsed brain tumors.

View abstract.

BMC Complement Med Ther.

Dietary supplements are not regulated in the U.S. For that reason, what's in some products may differ from what the label says. Complement Ther Med.

Am J Physiol Gastrointest Liver Physiol 2005;288:G798-808.

Sengupta K, Alluri KV, Satish AR, et al. 6-28-2000;25(3):241-244. Clinical trials have shown beneficial evidence for boswellia for all of the above uses but of varying consistency and reliability.